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Fenartil Brand names, Fenartil Analogs

Fenartil Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenartil Chemical_Formula

C19H20N2O2

Fenartil RX_link

No information avaliable

Fenartil fda sheet

Fenartil msds (material safety sheet)

Fenartil MSDS

Fenartil Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenartil Molecular Weight

308.374 g/mol

Fenartil Melting Point

105 oC

Fenartil H2O Solubility

47.5 mg/L

Fenartil State

Solid

Fenartil LogP

4.214

Fenartil Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenartil Indication

For the treatment of backache and ankylosing spondylitis

Fenartil Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenartil Absorption

No information avaliable

Fenartil side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenartil Patient Information

No information avaliable

Fenartil Organisms Affected

Humans and other mammals