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Eributazone Brand names, Eributazone Analogs

Eributazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Eributazone Chemical_Formula


Eributazone RX_link

No information avaliable

Eributazone fda sheet

Eributazone msds (material safety sheet)

Eributazone MSDS

Eributazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Eributazone Molecular Weight

308.374 g/mol

Eributazone Melting Point

105 oC

Eributazone H2O Solubility

47.5 mg/L

Eributazone State


Eributazone LogP


Eributazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Eributazone Indication

For the treatment of backache and ankylosing spondylitis

Eributazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Eributazone Absorption

No information avaliable

Eributazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Eributazone Patient Information

No information avaliable

Eributazone Organisms Affected

Humans and other mammals