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Chembutazone Brand names, Chembutazone Analogs

Chembutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Chembutazone Chemical_Formula


Chembutazone RX_link

No information avaliable

Chembutazone fda sheet

Chembutazone msds (material safety sheet)

Chembutazone MSDS

Chembutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Chembutazone Molecular Weight

308.374 g/mol

Chembutazone Melting Point

105 oC

Chembutazone H2O Solubility

47.5 mg/L

Chembutazone State


Chembutazone LogP


Chembutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Chembutazone Indication

For the treatment of backache and ankylosing spondylitis

Chembutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Chembutazone Absorption

No information avaliable

Chembutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Chembutazone Patient Information

No information avaliable

Chembutazone Organisms Affected

Humans and other mammals