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Fenibutasan Brand names, Fenibutasan Analogs

Fenibutasan Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenibutasan Chemical_Formula

C19H20N2O2

Fenibutasan RX_link

No information avaliable

Fenibutasan fda sheet

Fenibutasan msds (material safety sheet)

Fenibutasan MSDS

Fenibutasan Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenibutasan Molecular Weight

308.374 g/mol

Fenibutasan Melting Point

105 oC

Fenibutasan H2O Solubility

47.5 mg/L

Fenibutasan State

Solid

Fenibutasan LogP

4.214

Fenibutasan Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenibutasan Indication

For the treatment of backache and ankylosing spondylitis

Fenibutasan Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenibutasan Absorption

No information avaliable

Fenibutasan side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenibutasan Patient Information

No information avaliable

Fenibutasan Organisms Affected

Humans and other mammals