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Butiwas-Simple Brand names, Butiwas-Simple Analogs

Butiwas-Simple Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butiwas-Simple Chemical_Formula


Butiwas-Simple RX_link

No information avaliable

Butiwas-Simple fda sheet

Butiwas-Simple msds (material safety sheet)

Butiwas-Simple MSDS

Butiwas-Simple Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butiwas-Simple Molecular Weight

308.374 g/mol

Butiwas-Simple Melting Point

105 oC

Butiwas-Simple H2O Solubility

47.5 mg/L

Butiwas-Simple State


Butiwas-Simple LogP


Butiwas-Simple Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butiwas-Simple Indication

For the treatment of backache and ankylosing spondylitis

Butiwas-Simple Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butiwas-Simple Absorption

No information avaliable

Butiwas-Simple side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butiwas-Simple Patient Information

No information avaliable

Butiwas-Simple Organisms Affected

Humans and other mammals