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Intalbut Brand names, Intalbut Analogs

Intalbut Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Intalbut Chemical_Formula


Intalbut RX_link

No information avaliable

Intalbut fda sheet

Intalbut msds (material safety sheet)

Intalbut MSDS

Intalbut Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Intalbut Molecular Weight

308.374 g/mol

Intalbut Melting Point

105 oC

Intalbut H2O Solubility

47.5 mg/L

Intalbut State


Intalbut LogP


Intalbut Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Intalbut Indication

For the treatment of backache and ankylosing spondylitis

Intalbut Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Intalbut Absorption

No information avaliable

Intalbut side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Intalbut Patient Information

No information avaliable

Intalbut Organisms Affected

Humans and other mammals