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Butidiona Brand names, Butidiona Analogs

Butidiona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butidiona Chemical_Formula


Butidiona RX_link

No information avaliable

Butidiona fda sheet

Butidiona msds (material safety sheet)

Butidiona MSDS

Butidiona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butidiona Molecular Weight

308.374 g/mol

Butidiona Melting Point

105 oC

Butidiona H2O Solubility

47.5 mg/L

Butidiona State


Butidiona LogP


Butidiona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butidiona Indication

For the treatment of backache and ankylosing spondylitis

Butidiona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butidiona Absorption

No information avaliable

Butidiona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butidiona Patient Information

No information avaliable

Butidiona Organisms Affected

Humans and other mammals