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Intrabutazone Brand names, Intrabutazone Analogs

Intrabutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Intrabutazone Chemical_Formula


Intrabutazone RX_link

No information avaliable

Intrabutazone fda sheet

Intrabutazone msds (material safety sheet)

Intrabutazone MSDS

Intrabutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Intrabutazone Molecular Weight

308.374 g/mol

Intrabutazone Melting Point

105 oC

Intrabutazone H2O Solubility

47.5 mg/L

Intrabutazone State


Intrabutazone LogP


Intrabutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Intrabutazone Indication

For the treatment of backache and ankylosing spondylitis

Intrabutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Intrabutazone Absorption

No information avaliable

Intrabutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Intrabutazone Patient Information

No information avaliable

Intrabutazone Organisms Affected

Humans and other mammals