Rubatone
Rubatone Brand names, Rubatone Analogs
- 'Esteve'
- Alindor
- Alka Butazolidin
- Alkabutazona
- Alqoverin
- Ambene
- Anerval
- Anpuzone
- Antadol
- Anuspiramin
- Apo-Phenylbutazone
- Arthrizon
- Artizin
- Artrizin
- Artrizone
- Artropan
- Azdid
- Azobutyl
- Azolid
- B.T.Z.
- Benzone
- Betazed
- Bizolin
- Bizolin 200
- Bunetzone
- Busone
- Buta Phen
- Butacompren
- Butacote
- Butadion
- Butadiona
- Butadione
- Butagesic
- Butalan
- Butalgina
- Butalidon
- Butaluy
- Butapirazol
- Butapirazole
- Butapyrazole
- Butarecbon
- Butartril
- Butartrina
- Butatron
- Butazina
- Butazolidin
- Butazolidine
- Butazona
- Butazone
- Bute
- Butidiona
- Butiwas-Simple
- Butone
- Butoz
- Butylpyrin
- Buvetzone
- Buzon
- Chembutazone
- Cotylbutazone
- Digibutina
- Diossidone
- Diozol
- Diphebuzol
- Diphenylbutazone
- Ecobutazone
- Elmedal
- Equi Bute
- Equipalazone
- Eributazone
- Exrheudon N
- Febuzina
- Fenartil
- Fenibutal
- Fenibutasan
- Fenibutazona
- Fenibutol
- Fenilbutazona
- Fenilbutina
- Fenilbutine
- Fenilidina
- Fenotone
- Fenylbutazon
- Flexazone
- Ia-But
- Intalbut
- Intrabutazone
- Intrazone
- Ipsoflame
- Kadol
- Lingel
- Malgesic
- Mepha-Butazon
- Mephabutazon
- Mephabutazone
- Merizone
- Nadazone
- Nadozone
- Neo-Zoline
- Novophenyl
- PBZ
- Phebuzin
- Phebuzine
- Phenbutazol
- Phenbutazone
- Phenopyrine
- Phenyl-Mobuzon
- Phenylbutaz
- Phenylbutazonum
- Phenyzene
- Phenyzone
- Pirarreumol "B"
- Pirarreumol B
- Praecirheumin
- Pyrabutol
- Pyrazolidin
- Rectofasa
- Reudo
- Reudox
- Reumasyl
- Reumazin
- Reumazol
- Reumune
- Reumuzol
- Reupolar
- Robizon-V
- Robizone
- Robizone-V
- Rubatone
- Scanbutazone
- Schemergin
- Shigrodin
- Tazone
- Tencodyne
- Tetnor
- Tevcodyne
- Therazone
- Ticinil
- Todalgil
- Usaf Ge-15
- Uzone
- VAC-10
- Wescozone
- Zolaphen
- Zolidinum
- Zorane
Rubatone Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Rubatone Chemical_Formula
C19H20N2O2
Rubatone RX_link
No information avaliable
Rubatone fda sheet
Rubatone msds (material safety sheet)
Rubatone Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Rubatone Molecular Weight
308.374 g/mol
Rubatone Melting Point
105 oC
Rubatone H2O Solubility
47.5 mg/L
Rubatone State
Solid
Rubatone LogP
4.214
Rubatone Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Rubatone Indication
For the treatment of backache and ankylosing spondylitis
Rubatone Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Rubatone Absorption
No information avaliable
Rubatone side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Rubatone Patient Information
No information avaliable
Rubatone Organisms Affected
Humans and other mammals
