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Butazona Brand names, Butazona Analogs

Butazona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butazona Chemical_Formula

C19H20N2O2

Butazona RX_link

No information avaliable

Butazona fda sheet

Butazona msds (material safety sheet)

Butazona MSDS

Butazona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butazona Molecular Weight

308.374 g/mol

Butazona Melting Point

105 oC

Butazona H2O Solubility

47.5 mg/L

Butazona State

Solid

Butazona LogP

4.214

Butazona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butazona Indication

For the treatment of backache and ankylosing spondylitis

Butazona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butazona Absorption

No information avaliable

Butazona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butazona Patient Information

No information avaliable

Butazona Organisms Affected

Humans and other mammals