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Cotylbutazone Brand names, Cotylbutazone Analogs

Cotylbutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Cotylbutazone Chemical_Formula


Cotylbutazone RX_link

No information avaliable

Cotylbutazone fda sheet

Cotylbutazone msds (material safety sheet)

Cotylbutazone MSDS

Cotylbutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Cotylbutazone Molecular Weight

308.374 g/mol

Cotylbutazone Melting Point

105 oC

Cotylbutazone H2O Solubility

47.5 mg/L

Cotylbutazone State


Cotylbutazone LogP


Cotylbutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Cotylbutazone Indication

For the treatment of backache and ankylosing spondylitis

Cotylbutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Cotylbutazone Absorption

No information avaliable

Cotylbutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Cotylbutazone Patient Information

No information avaliable

Cotylbutazone Organisms Affected

Humans and other mammals