Diossidone en es it fr

Diossidone Brand names, Diossidone Analogs

Diossidone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Diossidone Chemical_Formula


Diossidone RX_link

No information avaliable

Diossidone fda sheet

Diossidone msds (material safety sheet)

Diossidone MSDS

Diossidone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Diossidone Molecular Weight

308.374 g/mol

Diossidone Melting Point

105 oC

Diossidone H2O Solubility

47.5 mg/L

Diossidone State


Diossidone LogP


Diossidone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Diossidone Indication

For the treatment of backache and ankylosing spondylitis

Diossidone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Diossidone Absorption

No information avaliable

Diossidone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Diossidone Patient Information

No information avaliable

Diossidone Organisms Affected

Humans and other mammals