Arthrizon en es it fr

Arthrizon Brand names, Arthrizon Analogs

Arthrizon Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Arthrizon Chemical_Formula


Arthrizon RX_link

No information avaliable

Arthrizon fda sheet

Arthrizon msds (material safety sheet)

Arthrizon MSDS

Arthrizon Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Arthrizon Molecular Weight

308.374 g/mol

Arthrizon Melting Point

105 oC

Arthrizon H2O Solubility

47.5 mg/L

Arthrizon State


Arthrizon LogP


Arthrizon Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Arthrizon Indication

For the treatment of backache and ankylosing spondylitis

Arthrizon Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Arthrizon Absorption

No information avaliable

Arthrizon side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Arthrizon Patient Information

No information avaliable

Arthrizon Organisms Affected

Humans and other mammals