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Diphenylbutazone Brand names, Diphenylbutazone Analogs

Diphenylbutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Diphenylbutazone Chemical_Formula


Diphenylbutazone RX_link

No information avaliable

Diphenylbutazone fda sheet

Diphenylbutazone msds (material safety sheet)

Diphenylbutazone MSDS

Diphenylbutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Diphenylbutazone Molecular Weight

308.374 g/mol

Diphenylbutazone Melting Point

105 oC

Diphenylbutazone H2O Solubility

47.5 mg/L

Diphenylbutazone State


Diphenylbutazone LogP


Diphenylbutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Diphenylbutazone Indication

For the treatment of backache and ankylosing spondylitis

Diphenylbutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Diphenylbutazone Absorption

No information avaliable

Diphenylbutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Diphenylbutazone Patient Information

No information avaliable

Diphenylbutazone Organisms Affected

Humans and other mammals