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Elmedal Brand names, Elmedal Analogs

Elmedal Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Elmedal Chemical_Formula

C19H20N2O2

Elmedal RX_link

No information avaliable

Elmedal fda sheet

Elmedal msds (material safety sheet)

Elmedal MSDS

Elmedal Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Elmedal Molecular Weight

308.374 g/mol

Elmedal Melting Point

105 oC

Elmedal H2O Solubility

47.5 mg/L

Elmedal State

Solid

Elmedal LogP

4.214

Elmedal Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Elmedal Indication

For the treatment of backache and ankylosing spondylitis

Elmedal Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Elmedal Absorption

No information avaliable

Elmedal side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Elmedal Patient Information

No information avaliable

Elmedal Organisms Affected

Humans and other mammals