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Diozol Brand names, Diozol Analogs

Diozol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Diozol Chemical_Formula


Diozol RX_link

No information avaliable

Diozol fda sheet

Diozol msds (material safety sheet)

Diozol MSDS

Diozol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Diozol Molecular Weight

308.374 g/mol

Diozol Melting Point

105 oC

Diozol H2O Solubility

47.5 mg/L

Diozol State


Diozol LogP


Diozol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Diozol Indication

For the treatment of backache and ankylosing spondylitis

Diozol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Diozol Absorption

No information avaliable

Diozol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Diozol Patient Information

No information avaliable

Diozol Organisms Affected

Humans and other mammals