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Fenilbutina Brand names, Fenilbutina Analogs

Fenilbutina Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenilbutina Chemical_Formula


Fenilbutina RX_link

No information avaliable

Fenilbutina fda sheet

Fenilbutina msds (material safety sheet)

Fenilbutina MSDS

Fenilbutina Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenilbutina Molecular Weight

308.374 g/mol

Fenilbutina Melting Point

105 oC

Fenilbutina H2O Solubility

47.5 mg/L

Fenilbutina State


Fenilbutina LogP


Fenilbutina Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenilbutina Indication

For the treatment of backache and ankylosing spondylitis

Fenilbutina Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenilbutina Absorption

No information avaliable

Fenilbutina side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenilbutina Patient Information

No information avaliable

Fenilbutina Organisms Affected

Humans and other mammals