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Butoz Brand names, Butoz Analogs

Butoz Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butoz Chemical_Formula


Butoz RX_link

No information avaliable

Butoz fda sheet

Butoz msds (material safety sheet)

Butoz MSDS

Butoz Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butoz Molecular Weight

308.374 g/mol

Butoz Melting Point

105 oC

Butoz H2O Solubility

47.5 mg/L

Butoz State


Butoz LogP


Butoz Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butoz Indication

For the treatment of backache and ankylosing spondylitis

Butoz Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butoz Absorption

No information avaliable

Butoz side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butoz Patient Information

No information avaliable

Butoz Organisms Affected

Humans and other mammals