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Butazolidin Brand names, Butazolidin Analogs

Butazolidin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butazolidin Chemical_Formula


Butazolidin RX_link

No information avaliable

Butazolidin fda sheet

Butazolidin msds (material safety sheet)

Butazolidin MSDS

Butazolidin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butazolidin Molecular Weight

308.374 g/mol

Butazolidin Melting Point

105 oC

Butazolidin H2O Solubility

47.5 mg/L

Butazolidin State


Butazolidin LogP


Butazolidin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butazolidin Indication

For the treatment of backache and ankylosing spondylitis

Butazolidin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butazolidin Absorption

No information avaliable

Butazolidin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butazolidin Patient Information

No information avaliable

Butazolidin Organisms Affected

Humans and other mammals