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Phenbutazone Brand names, Phenbutazone Analogs

Phenbutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenbutazone Chemical_Formula


Phenbutazone RX_link

No information avaliable

Phenbutazone fda sheet

Phenbutazone msds (material safety sheet)

Phenbutazone MSDS

Phenbutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenbutazone Molecular Weight

308.374 g/mol

Phenbutazone Melting Point

105 oC

Phenbutazone H2O Solubility

47.5 mg/L

Phenbutazone State


Phenbutazone LogP


Phenbutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenbutazone Indication

For the treatment of backache and ankylosing spondylitis

Phenbutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenbutazone Absorption

No information avaliable

Phenbutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenbutazone Patient Information

No information avaliable

Phenbutazone Organisms Affected

Humans and other mammals