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Equipalazone Brand names, Equipalazone Analogs

Equipalazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Equipalazone Chemical_Formula

C19H20N2O2

Equipalazone RX_link

No information avaliable

Equipalazone fda sheet

Equipalazone msds (material safety sheet)

Equipalazone MSDS

Equipalazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Equipalazone Molecular Weight

308.374 g/mol

Equipalazone Melting Point

105 oC

Equipalazone H2O Solubility

47.5 mg/L

Equipalazone State

Solid

Equipalazone LogP

4.214

Equipalazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Equipalazone Indication

For the treatment of backache and ankylosing spondylitis

Equipalazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Equipalazone Absorption

No information avaliable

Equipalazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Equipalazone Patient Information

No information avaliable

Equipalazone Organisms Affected

Humans and other mammals