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Tetnor Brand names, Tetnor Analogs

Tetnor Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Tetnor Chemical_Formula

C19H20N2O2

Tetnor RX_link

No information avaliable

Tetnor fda sheet

Tetnor msds (material safety sheet)

Tetnor MSDS

Tetnor Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Tetnor Molecular Weight

308.374 g/mol

Tetnor Melting Point

105 oC

Tetnor H2O Solubility

47.5 mg/L

Tetnor State

Solid

Tetnor LogP

4.214

Tetnor Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Tetnor Indication

For the treatment of backache and ankylosing spondylitis

Tetnor Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Tetnor Absorption

No information avaliable

Tetnor side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Tetnor Patient Information

No information avaliable

Tetnor Organisms Affected

Humans and other mammals