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Fenotone Brand names, Fenotone Analogs

Fenotone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenotone Chemical_Formula

C19H20N2O2

Fenotone RX_link

No information avaliable

Fenotone fda sheet

Fenotone msds (material safety sheet)

Fenotone MSDS

Fenotone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenotone Molecular Weight

308.374 g/mol

Fenotone Melting Point

105 oC

Fenotone H2O Solubility

47.5 mg/L

Fenotone State

Solid

Fenotone LogP

4.214

Fenotone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenotone Indication

For the treatment of backache and ankylosing spondylitis

Fenotone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenotone Absorption

No information avaliable

Fenotone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenotone Patient Information

No information avaliable

Fenotone Organisms Affected

Humans and other mammals