Ia-But en es it fr

Ia-But Brand names, Ia-But Analogs

Ia-But Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Ia-But Chemical_Formula


Ia-But RX_link

No information avaliable

Ia-But fda sheet

Ia-But msds (material safety sheet)


Ia-But Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Ia-But Molecular Weight

308.374 g/mol

Ia-But Melting Point

105 oC

Ia-But H2O Solubility

47.5 mg/L

Ia-But State


Ia-But LogP


Ia-But Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Ia-But Indication

For the treatment of backache and ankylosing spondylitis

Ia-But Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Ia-But Absorption

No information avaliable

Ia-But side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Ia-But Patient Information

No information avaliable

Ia-But Organisms Affected

Humans and other mammals