Ia-But
Ia-But Brand names, Ia-But Analogs
- 'Esteve'
- Alindor
- Alka Butazolidin
- Alkabutazona
- Alqoverin
- Ambene
- Anerval
- Anpuzone
- Antadol
- Anuspiramin
- Apo-Phenylbutazone
- Arthrizon
- Artizin
- Artrizin
- Artrizone
- Artropan
- Azdid
- Azobutyl
- Azolid
- B.T.Z.
- Benzone
- Betazed
- Bizolin
- Bizolin 200
- Bunetzone
- Busone
- Buta Phen
- Butacompren
- Butacote
- Butadion
- Butadiona
- Butadione
- Butagesic
- Butalan
- Butalgina
- Butalidon
- Butaluy
- Butapirazol
- Butapirazole
- Butapyrazole
- Butarecbon
- Butartril
- Butartrina
- Butatron
- Butazina
- Butazolidin
- Butazolidine
- Butazona
- Butazone
- Bute
- Butidiona
- Butiwas-Simple
- Butone
- Butoz
- Butylpyrin
- Buvetzone
- Buzon
- Chembutazone
- Cotylbutazone
- Digibutina
- Diossidone
- Diozol
- Diphebuzol
- Diphenylbutazone
- Ecobutazone
- Elmedal
- Equi Bute
- Equipalazone
- Eributazone
- Exrheudon N
- Febuzina
- Fenartil
- Fenibutal
- Fenibutasan
- Fenibutazona
- Fenibutol
- Fenilbutazona
- Fenilbutina
- Fenilbutine
- Fenilidina
- Fenotone
- Fenylbutazon
- Flexazone
- Ia-But
- Intalbut
- Intrabutazone
- Intrazone
- Ipsoflame
- Kadol
- Lingel
- Malgesic
- Mepha-Butazon
- Mephabutazon
- Mephabutazone
- Merizone
- Nadazone
- Nadozone
- Neo-Zoline
- Novophenyl
- PBZ
- Phebuzin
- Phebuzine
- Phenbutazol
- Phenbutazone
- Phenopyrine
- Phenyl-Mobuzon
- Phenylbutaz
- Phenylbutazonum
- Phenyzene
- Phenyzone
- Pirarreumol "B"
- Pirarreumol B
- Praecirheumin
- Pyrabutol
- Pyrazolidin
- Rectofasa
- Reudo
- Reudox
- Reumasyl
- Reumazin
- Reumazol
- Reumune
- Reumuzol
- Reupolar
- Robizon-V
- Robizone
- Robizone-V
- Rubatone
- Scanbutazone
- Schemergin
- Shigrodin
- Tazone
- Tencodyne
- Tetnor
- Tevcodyne
- Therazone
- Ticinil
- Todalgil
- Usaf Ge-15
- Uzone
- VAC-10
- Wescozone
- Zolaphen
- Zolidinum
- Zorane
Ia-But Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Ia-But Chemical_Formula
C19H20N2O2
Ia-But RX_link
No information avaliable
Ia-But fda sheet
Ia-But msds (material safety sheet)
Ia-But Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Ia-But Molecular Weight
308.374 g/mol
Ia-But Melting Point
105 oC
Ia-But H2O Solubility
47.5 mg/L
Ia-But State
Solid
Ia-But LogP
4.214
Ia-But Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Ia-But Indication
For the treatment of backache and ankylosing spondylitis
Ia-But Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Ia-But Absorption
No information avaliable
Ia-But side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Ia-But Patient Information
No information avaliable
Ia-But Organisms Affected
Humans and other mammals
