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Bute Brand names, Bute Analogs

Bute Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Bute Chemical_Formula


Bute RX_link

No information avaliable

Bute fda sheet

Bute msds (material safety sheet)


Bute Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Bute Molecular Weight

308.374 g/mol

Bute Melting Point

105 oC

Bute H2O Solubility

47.5 mg/L

Bute State


Bute LogP


Bute Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Bute Indication

For the treatment of backache and ankylosing spondylitis

Bute Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Bute Absorption

No information avaliable

Bute side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Bute Patient Information

No information avaliable

Bute Organisms Affected

Humans and other mammals