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Digibutina Brand names, Digibutina Analogs

Digibutina Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Digibutina Chemical_Formula

C19H20N2O2

Digibutina RX_link

No information avaliable

Digibutina fda sheet

Digibutina msds (material safety sheet)

Digibutina MSDS

Digibutina Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Digibutina Molecular Weight

308.374 g/mol

Digibutina Melting Point

105 oC

Digibutina H2O Solubility

47.5 mg/L

Digibutina State

Solid

Digibutina LogP

4.214

Digibutina Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Digibutina Indication

For the treatment of backache and ankylosing spondylitis

Digibutina Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Digibutina Absorption

No information avaliable

Digibutina side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Digibutina Patient Information

No information avaliable

Digibutina Organisms Affected

Humans and other mammals