Reudox
Brand names,
Reudox
Analogs
Reudox
Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Reudox
Chemical_Formula
C19H20N2O2
Reudox
RX_link
No information avaliable
Reudox
fda sheet
Reudox
msds (material safety sheet)
Reudox
Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Reudox
Molecular Weight
308.374 g/mol
Reudox
Melting Point
105 oC
Reudox
H2O Solubility
47.5 mg/L
Reudox
State
Solid
Reudox
LogP
4.214
Reudox
Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Reudox
Indication
For the treatment of backache and ankylosing spondylitis
Reudox
Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Reudox
Absorption
No information avaliable
Reudox
side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Reudox
Patient Information
No information avaliable
Reudox
Organisms Affected
Humans and other mammals