Zolaphen en es it fr

Zolaphen Brand names, Zolaphen Analogs

Zolaphen Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Zolaphen Chemical_Formula


Zolaphen RX_link

No information avaliable

Zolaphen fda sheet

Zolaphen msds (material safety sheet)

Zolaphen MSDS

Zolaphen Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Zolaphen Molecular Weight

308.374 g/mol

Zolaphen Melting Point

105 oC

Zolaphen H2O Solubility

47.5 mg/L

Zolaphen State


Zolaphen LogP


Zolaphen Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Zolaphen Indication

For the treatment of backache and ankylosing spondylitis

Zolaphen Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Zolaphen Absorption

No information avaliable

Zolaphen side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Zolaphen Patient Information

No information avaliable

Zolaphen Organisms Affected

Humans and other mammals