Zolidinum en es it fr

Zolidinum Brand names, Zolidinum Analogs

Zolidinum Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Zolidinum Chemical_Formula


Zolidinum RX_link

No information avaliable

Zolidinum fda sheet

Zolidinum msds (material safety sheet)

Zolidinum MSDS

Zolidinum Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Zolidinum Molecular Weight

308.374 g/mol

Zolidinum Melting Point

105 oC

Zolidinum H2O Solubility

47.5 mg/L

Zolidinum State


Zolidinum LogP


Zolidinum Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Zolidinum Indication

For the treatment of backache and ankylosing spondylitis

Zolidinum Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Zolidinum Absorption

No information avaliable

Zolidinum side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Zolidinum Patient Information

No information avaliable

Zolidinum Organisms Affected

Humans and other mammals