Pyrazolidin en es it fr

Pyrazolidin Brand names, Pyrazolidin Analogs

Pyrazolidin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Pyrazolidin Chemical_Formula


Pyrazolidin RX_link

No information avaliable

Pyrazolidin fda sheet

Pyrazolidin msds (material safety sheet)

Pyrazolidin MSDS

Pyrazolidin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Pyrazolidin Molecular Weight

308.374 g/mol

Pyrazolidin Melting Point

105 oC

Pyrazolidin H2O Solubility

47.5 mg/L

Pyrazolidin State


Pyrazolidin LogP


Pyrazolidin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Pyrazolidin Indication

For the treatment of backache and ankylosing spondylitis

Pyrazolidin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Pyrazolidin Absorption

No information avaliable

Pyrazolidin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Pyrazolidin Patient Information

No information avaliable

Pyrazolidin Organisms Affected

Humans and other mammals