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Uzone Brand names, Uzone Analogs

Uzone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Uzone Chemical_Formula


Uzone RX_link

No information avaliable

Uzone fda sheet

Uzone msds (material safety sheet)

Uzone MSDS

Uzone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Uzone Molecular Weight

308.374 g/mol

Uzone Melting Point

105 oC

Uzone H2O Solubility

47.5 mg/L

Uzone State


Uzone LogP


Uzone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Uzone Indication

For the treatment of backache and ankylosing spondylitis

Uzone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Uzone Absorption

No information avaliable

Uzone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Uzone Patient Information

No information avaliable

Uzone Organisms Affected

Humans and other mammals