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Phenyzone Brand names, Phenyzone Analogs

Phenyzone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenyzone Chemical_Formula


Phenyzone RX_link

No information avaliable

Phenyzone fda sheet

Phenyzone msds (material safety sheet)

Phenyzone MSDS

Phenyzone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenyzone Molecular Weight

308.374 g/mol

Phenyzone Melting Point

105 oC

Phenyzone H2O Solubility

47.5 mg/L

Phenyzone State


Phenyzone LogP


Phenyzone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenyzone Indication

For the treatment of backache and ankylosing spondylitis

Phenyzone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenyzone Absorption

No information avaliable

Phenyzone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenyzone Patient Information

No information avaliable

Phenyzone Organisms Affected

Humans and other mammals