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Nadazone Brand names, Nadazone Analogs

Nadazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Nadazone Chemical_Formula


Nadazone RX_link

No information avaliable

Nadazone fda sheet

Nadazone msds (material safety sheet)

Nadazone MSDS

Nadazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Nadazone Molecular Weight

308.374 g/mol

Nadazone Melting Point

105 oC

Nadazone H2O Solubility

47.5 mg/L

Nadazone State


Nadazone LogP


Nadazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Nadazone Indication

For the treatment of backache and ankylosing spondylitis

Nadazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Nadazone Absorption

No information avaliable

Nadazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Nadazone Patient Information

No information avaliable

Nadazone Organisms Affected

Humans and other mammals