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Antadol Brand names, Antadol Analogs

Antadol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Antadol Chemical_Formula


Antadol RX_link

No information avaliable

Antadol fda sheet

Antadol msds (material safety sheet)

Antadol MSDS

Antadol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Antadol Molecular Weight

308.374 g/mol

Antadol Melting Point

105 oC

Antadol H2O Solubility

47.5 mg/L

Antadol State


Antadol LogP


Antadol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Antadol Indication

For the treatment of backache and ankylosing spondylitis

Antadol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Antadol Absorption

No information avaliable

Antadol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Antadol Patient Information

No information avaliable

Antadol Organisms Affected

Humans and other mammals