Alkabutazona en es it fr

Alkabutazona Brand names, Alkabutazona Analogs

Alkabutazona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Alkabutazona Chemical_Formula


Alkabutazona RX_link

No information avaliable

Alkabutazona fda sheet

Alkabutazona msds (material safety sheet)

Alkabutazona MSDS

Alkabutazona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Alkabutazona Molecular Weight

308.374 g/mol

Alkabutazona Melting Point

105 oC

Alkabutazona H2O Solubility

47.5 mg/L

Alkabutazona State


Alkabutazona LogP


Alkabutazona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Alkabutazona Indication

For the treatment of backache and ankylosing spondylitis

Alkabutazona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Alkabutazona Absorption

No information avaliable

Alkabutazona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Alkabutazona Patient Information

No information avaliable

Alkabutazona Organisms Affected

Humans and other mammals