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Butalgina Brand names, Butalgina Analogs

Butalgina Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butalgina Chemical_Formula

C19H20N2O2

Butalgina RX_link

No information avaliable

Butalgina fda sheet

Butalgina msds (material safety sheet)

Butalgina MSDS

Butalgina Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butalgina Molecular Weight

308.374 g/mol

Butalgina Melting Point

105 oC

Butalgina H2O Solubility

47.5 mg/L

Butalgina State

Solid

Butalgina LogP

4.214

Butalgina Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butalgina Indication

For the treatment of backache and ankylosing spondylitis

Butalgina Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butalgina Absorption

No information avaliable

Butalgina side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butalgina Patient Information

No information avaliable

Butalgina Organisms Affected

Humans and other mammals