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Butazone Brand names, Butazone Analogs

Butazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butazone Chemical_Formula


Butazone RX_link

No information avaliable

Butazone fda sheet

Butazone msds (material safety sheet)

Butazone MSDS

Butazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butazone Molecular Weight

308.374 g/mol

Butazone Melting Point

105 oC

Butazone H2O Solubility

47.5 mg/L

Butazone State


Butazone LogP


Butazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butazone Indication

For the treatment of backache and ankylosing spondylitis

Butazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butazone Absorption

No information avaliable

Butazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butazone Patient Information

No information avaliable

Butazone Organisms Affected

Humans and other mammals