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Phenopyrine en es it fr

Phenopyrine Brand names, Phenopyrine Analogs

Phenopyrine Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenopyrine Chemical_Formula

C19H20N2O2

Phenopyrine RX_link

No information avaliable

Phenopyrine fda sheet

Phenopyrine msds (material safety sheet)

Phenopyrine MSDS

Phenopyrine Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenopyrine Molecular Weight

308.374 g/mol

Phenopyrine Melting Point

105 oC

Phenopyrine H2O Solubility

47.5 mg/L

Phenopyrine State

Solid

Phenopyrine LogP

4.214

Phenopyrine Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenopyrine Indication

For the treatment of backache and ankylosing spondylitis

Phenopyrine Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenopyrine Absorption

No information avaliable

Phenopyrine side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenopyrine Patient Information

No information avaliable

Phenopyrine Organisms Affected

Humans and other mammals