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Fenilbutine Brand names, Fenilbutine Analogs

Fenilbutine Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenilbutine Chemical_Formula


Fenilbutine RX_link

No information avaliable

Fenilbutine fda sheet

Fenilbutine msds (material safety sheet)

Fenilbutine MSDS

Fenilbutine Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenilbutine Molecular Weight

308.374 g/mol

Fenilbutine Melting Point

105 oC

Fenilbutine H2O Solubility

47.5 mg/L

Fenilbutine State


Fenilbutine LogP


Fenilbutine Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenilbutine Indication

For the treatment of backache and ankylosing spondylitis

Fenilbutine Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenilbutine Absorption

No information avaliable

Fenilbutine side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenilbutine Patient Information

No information avaliable

Fenilbutine Organisms Affected

Humans and other mammals