Mepha-Butazon en es it fr

Mepha-Butazon Brand names, Mepha-Butazon Analogs

Mepha-Butazon Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Mepha-Butazon Chemical_Formula


Mepha-Butazon RX_link

No information avaliable

Mepha-Butazon fda sheet

Mepha-Butazon msds (material safety sheet)

Mepha-Butazon MSDS

Mepha-Butazon Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Mepha-Butazon Molecular Weight

308.374 g/mol

Mepha-Butazon Melting Point

105 oC

Mepha-Butazon H2O Solubility

47.5 mg/L

Mepha-Butazon State


Mepha-Butazon LogP


Mepha-Butazon Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Mepha-Butazon Indication

For the treatment of backache and ankylosing spondylitis

Mepha-Butazon Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Mepha-Butazon Absorption

No information avaliable

Mepha-Butazon side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Mepha-Butazon Patient Information

No information avaliable

Mepha-Butazon Organisms Affected

Humans and other mammals