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Malgesic Brand names, Malgesic Analogs

Malgesic Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Malgesic Chemical_Formula


Malgesic RX_link

No information avaliable

Malgesic fda sheet

Malgesic msds (material safety sheet)

Malgesic MSDS

Malgesic Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Malgesic Molecular Weight

308.374 g/mol

Malgesic Melting Point

105 oC

Malgesic H2O Solubility

47.5 mg/L

Malgesic State


Malgesic LogP


Malgesic Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Malgesic Indication

For the treatment of backache and ankylosing spondylitis

Malgesic Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Malgesic Absorption

No information avaliable

Malgesic side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Malgesic Patient Information

No information avaliable

Malgesic Organisms Affected

Humans and other mammals