Malgesic
Malgesic Brand names, Malgesic Analogs
- 'Esteve'
- Alindor
- Alka Butazolidin
- Alkabutazona
- Alqoverin
- Ambene
- Anerval
- Anpuzone
- Antadol
- Anuspiramin
- Apo-Phenylbutazone
- Arthrizon
- Artizin
- Artrizin
- Artrizone
- Artropan
- Azdid
- Azobutyl
- Azolid
- B.T.Z.
- Benzone
- Betazed
- Bizolin
- Bizolin 200
- Bunetzone
- Busone
- Buta Phen
- Butacompren
- Butacote
- Butadion
- Butadiona
- Butadione
- Butagesic
- Butalan
- Butalgina
- Butalidon
- Butaluy
- Butapirazol
- Butapirazole
- Butapyrazole
- Butarecbon
- Butartril
- Butartrina
- Butatron
- Butazina
- Butazolidin
- Butazolidine
- Butazona
- Butazone
- Bute
- Butidiona
- Butiwas-Simple
- Butone
- Butoz
- Butylpyrin
- Buvetzone
- Buzon
- Chembutazone
- Cotylbutazone
- Digibutina
- Diossidone
- Diozol
- Diphebuzol
- Diphenylbutazone
- Ecobutazone
- Elmedal
- Equi Bute
- Equipalazone
- Eributazone
- Exrheudon N
- Febuzina
- Fenartil
- Fenibutal
- Fenibutasan
- Fenibutazona
- Fenibutol
- Fenilbutazona
- Fenilbutina
- Fenilbutine
- Fenilidina
- Fenotone
- Fenylbutazon
- Flexazone
- Ia-But
- Intalbut
- Intrabutazone
- Intrazone
- Ipsoflame
- Kadol
- Lingel
- Malgesic
- Mepha-Butazon
- Mephabutazon
- Mephabutazone
- Merizone
- Nadazone
- Nadozone
- Neo-Zoline
- Novophenyl
- PBZ
- Phebuzin
- Phebuzine
- Phenbutazol
- Phenbutazone
- Phenopyrine
- Phenyl-Mobuzon
- Phenylbutaz
- Phenylbutazonum
- Phenyzene
- Phenyzone
- Pirarreumol "B"
- Pirarreumol B
- Praecirheumin
- Pyrabutol
- Pyrazolidin
- Rectofasa
- Reudo
- Reudox
- Reumasyl
- Reumazin
- Reumazol
- Reumune
- Reumuzol
- Reupolar
- Robizon-V
- Robizone
- Robizone-V
- Rubatone
- Scanbutazone
- Schemergin
- Shigrodin
- Tazone
- Tencodyne
- Tetnor
- Tevcodyne
- Therazone
- Ticinil
- Todalgil
- Usaf Ge-15
- Uzone
- VAC-10
- Wescozone
- Zolaphen
- Zolidinum
- Zorane
Malgesic Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Malgesic Chemical_Formula
C19H20N2O2
Malgesic RX_link
No information avaliable
Malgesic fda sheet
Malgesic msds (material safety sheet)
Malgesic Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Malgesic Molecular Weight
308.374 g/mol
Malgesic Melting Point
105 oC
Malgesic H2O Solubility
47.5 mg/L
Malgesic State
Solid
Malgesic LogP
4.214
Malgesic Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Malgesic Indication
For the treatment of backache and ankylosing spondylitis
Malgesic Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Malgesic Absorption
No information avaliable
Malgesic side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Malgesic Patient Information
No information avaliable
Malgesic Organisms Affected
Humans and other mammals
