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Butacote Brand names, Butacote Analogs

Butacote Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butacote Chemical_Formula


Butacote RX_link

No information avaliable

Butacote fda sheet

Butacote msds (material safety sheet)

Butacote MSDS

Butacote Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butacote Molecular Weight

308.374 g/mol

Butacote Melting Point

105 oC

Butacote H2O Solubility

47.5 mg/L

Butacote State


Butacote LogP


Butacote Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butacote Indication

For the treatment of backache and ankylosing spondylitis

Butacote Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butacote Absorption

No information avaliable

Butacote side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butacote Patient Information

No information avaliable

Butacote Organisms Affected

Humans and other mammals