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Butalgin Brand names, Butalgin Analogs

Butalgin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butalgin Chemical_Formula

C19H20N2O2

Butalgin RX_link

No information avaliable

Butalgin fda sheet

Butalgin msds (material safety sheet)

Butalgin MSDS

Butalgin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butalgin Molecular Weight

308.374 g/mol

Butalgin Melting Point

105 oC

Butalgin H2O Solubility

47.5 mg/L

Butalgin State

Solid

Butalgin LogP

4.214

Butalgin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butalgin Indication

For the treatment of backache and ankylosing spondylitis

Butalgin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butalgin Absorption

No information avaliable

Butalgin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butalgin Patient Information

No information avaliable

Butalgin Organisms Affected

Humans and other mammals