Phenylbutazone en es it fr

Phenylbutazone Brand names, Phenylbutazone Analogs

Phenylbutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenylbutazone Chemical_Formula


Phenylbutazone RX_link

No information avaliable

Phenylbutazone fda sheet

Phenylbutazone msds (material safety sheet)

Phenylbutazone MSDS

Phenylbutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenylbutazone Molecular Weight

308.374 g/mol

Phenylbutazone Melting Point

105 oC

Phenylbutazone H2O Solubility

47.5 mg/L

Phenylbutazone State


Phenylbutazone LogP


Phenylbutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenylbutazone Indication

For the treatment of backache and ankylosing spondylitis

Phenylbutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenylbutazone Absorption

No information avaliable

Phenylbutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenylbutazone Patient Information

No information avaliable

Phenylbutazone Organisms Affected

Humans and other mammals