Tibison
Brand names,
Tibison
Analogs
Tibison
Brand Names Mixture
Tibison
Chemical_Formula
C19H24N2O3
Tibison
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tibison
fda sheet
Tibison
msds (material safety sheet)
Tibison
Synthesis Reference
No information avaliable
Tibison
Molecular Weight
328.406 g/mol
Tibison
Melting Point
195-196 oC
Tibison
H2O Solubility
20 mg/ml (HCl salt)
Tibison
State
Solid
Tibison
LogP
2.868
Tibison
Dosage Forms
Liquid; Tablet
Tibison
Indication
For the management of hypertension.
Tibison
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tibison
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tibison
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tibison
Patient Information
Tibison
Organisms Affected
Humans and other mammals