Chemiazid
Brand names,
Chemiazid
Analogs
Chemiazid
Brand Names Mixture
Chemiazid
Chemical_Formula
C19H24N2O3
Chemiazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Chemiazid
fda sheet
Chemiazid
msds (material safety sheet)
Chemiazid
Synthesis Reference
No information avaliable
Chemiazid
Molecular Weight
328.406 g/mol
Chemiazid
Melting Point
195-196 oC
Chemiazid
H2O Solubility
20 mg/ml (HCl salt)
Chemiazid
State
Solid
Chemiazid
LogP
2.868
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Dosage Forms
Liquid; Tablet
Chemiazid
Indication
For the management of hypertension.
Chemiazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Chemiazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Chemiazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Chemiazid
Patient Information
Chemiazid
Organisms Affected
Humans and other mammals