Nicozide
Brand names,
Nicozide
Analogs
Nicozide
Brand Names Mixture
Nicozide
Chemical_Formula
C19H24N2O3
Nicozide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Nicozide
fda sheet
Nicozide
msds (material safety sheet)
Nicozide
Synthesis Reference
No information avaliable
Nicozide
Molecular Weight
328.406 g/mol
Nicozide
Melting Point
195-196 oC
Nicozide
H2O Solubility
20 mg/ml (HCl salt)
Nicozide
State
Solid
Nicozide
LogP
2.868
Nicozide
Dosage Forms
Liquid; Tablet
Nicozide
Indication
For the management of hypertension.
Nicozide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Nicozide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Nicozide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Nicozide
Patient Information
Nicozide
Organisms Affected
Humans and other mammals