Tebexin
Brand names,
Tebexin
Analogs
Tebexin
Brand Names Mixture
Tebexin
Chemical_Formula
C19H24N2O3
Tebexin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tebexin
fda sheet
Tebexin
msds (material safety sheet)
Tebexin
Synthesis Reference
No information avaliable
Tebexin
Molecular Weight
328.406 g/mol
Tebexin
Melting Point
195-196 oC
Tebexin
H2O Solubility
20 mg/ml (HCl salt)
Tebexin
State
Solid
Tebexin
LogP
2.868
Tebexin
Dosage Forms
Liquid; Tablet
Tebexin
Indication
For the management of hypertension.
Tebexin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tebexin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tebexin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tebexin
Patient Information
Tebexin
Organisms Affected
Humans and other mammals