Diforin
Brand names,
Diforin
Analogs
Diforin
Brand Names Mixture
Diforin
Chemical_Formula
C19H24N2O3
Diforin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Diforin
fda sheet
Diforin
msds (material safety sheet)
Diforin
Synthesis Reference
No information avaliable
Diforin
Molecular Weight
328.406 g/mol
Diforin
Melting Point
195-196 oC
Diforin
H2O Solubility
20 mg/ml (HCl salt)
Diforin
State
Solid
Diforin
LogP
2.868
Diforin
Dosage Forms
Liquid; Tablet
Diforin
Indication
For the management of hypertension.
Diforin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Diforin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Diforin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Diforin
Patient Information
Diforin
Organisms Affected
Humans and other mammals