Tibazide
Brand names,
Tibazide
Analogs
Tibazide
Brand Names Mixture
Tibazide
Chemical_Formula
C19H24N2O3
Tibazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tibazide
fda sheet
Tibazide
msds (material safety sheet)
Tibazide
Synthesis Reference
No information avaliable
Tibazide
Molecular Weight
328.406 g/mol
Tibazide
Melting Point
195-196 oC
Tibazide
H2O Solubility
20 mg/ml (HCl salt)
Tibazide
State
Solid
Tibazide
LogP
2.868
Tibazide
Dosage Forms
Liquid; Tablet
Tibazide
Indication
For the management of hypertension.
Tibazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tibazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tibazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tibazide
Patient Information
Tibazide
Organisms Affected
Humans and other mammals